Impact-ionization field-effect-transistor based biosensors for ultra-sensitive detection of biomolecules
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چکیده
The phenomenon of impact-ionization is proposed to be leveraged for a novel biosensor design scheme for highly efficient electrical detection of biological species. Apart from self-consistent numerical simulations, an analytical formalism is also presented to provide physical insight into the working mechanism and performance of the proposed sensor. It is shown that using the impactionization field-effect-transistor (IFET) based biosensor, it is possible to obtain an increase in sensitivity of around 4 orders of magnitude at low biomolecule concentration and around 6 orders of magnitude at high biomolecule concentration compared to that in conventional FET (CFET) biosensors. Moreover, IFET biosensors can lead to significant reduction (around 2 orders of magnitude) in response time compared to CFET biosensors. VC 2013 AIP Publishing LLC. [http://dx.doi.org/10.1063/1.4804577]
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تاریخ انتشار 2013